3l8x: Difference between revisions

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{{Seed}}
[[Image:3l8x.png|left|200px]]
[[Image:3l8x.jpg|left|200px]]


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{{STRUCTURE_3l8x|  PDB=3l8x  |  SCENE=  }}  
{{STRUCTURE_3l8x|  PDB=3l8x  |  SCENE=  }}  


===P38 alpha kinase complexed with a pyrazolo-pyrimidine based inhibitor===
===P38 alpha kinase complexed with a pyrazolo-pyrimidine based inhibitor===


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{{ABSTRACT_PUBMED_18359226}}
{{ABSTRACT_PUBMED_18359226}}


==About this Structure==
==About this Structure==
3L8X is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3cg2 3cg2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L8X OCA].  
[[3l8x]] is a 1 chain structure of [[Mitogen-activated protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3cg2 3cg2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L8X OCA].  
 
==See Also==
*[[Mitogen-activated protein kinase|Mitogen-activated protein kinase]]


==Reference==
==Reference==
<ref group="xtra">PMID:18359226</ref><references group="xtra"/>
<ref group="xtra">PMID:018359226</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Mitogen-activated protein kinase]]
[[Category: Mitogen-activated protein kinase]]
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[[Category: Serine/threonine-protine kinase]]
[[Category: Serine/threonine-protine kinase]]
[[Category: Transferase]]
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar  3 15:48:49 2010''

Revision as of 09:23, 26 July 2012

File:3l8x.png

Template:STRUCTURE 3l8x

P38 alpha kinase complexed with a pyrazolo-pyrimidine based inhibitor

Template:ABSTRACT PUBMED 18359226

About this Structure

3l8x is a 1 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 3cg2. Full crystallographic information is available from OCA.

See Also

Reference

  1. Das J, Moquin RV, Pitt S, Zhang R, Shen DR, McIntyre KW, Gillooly K, Doweyko AM, Sack JS, Zhang H, Kiefer SE, Kish K, McKinnon M, Barrish JC, Dodd JH, Schieven GL, Leftheris K. Pyrazolo-pyrimidines: a novel heterocyclic scaffold for potent and selective p38 alpha inhibitors. Bioorg Med Chem Lett. 2008 Apr 15;18(8):2652-7. Epub 2008 Mar 10. PMID:18359226 doi:10.1016/j.bmcl.2008.03.019

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