3inf: Difference between revisions
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[[Image:3inf.png|left|200px]] | |||
[[Image:3inf. | |||
{{STRUCTURE_3inf| PDB=3inf | SCENE= }} | {{STRUCTURE_3inf| PDB=3inf | SCENE= }} | ||
===Bace1 with the aminohydantoin Compound 37=== | ===Bace1 with the aminohydantoin Compound 37=== | ||
{{ABSTRACT_PUBMED_19968289}} | {{ABSTRACT_PUBMED_19968289}} | ||
==About this Structure== | ==About this Structure== | ||
[[3inf]] is a 1 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3INF OCA]. | |||
==See Also== | |||
*[[Beta secretase|Beta secretase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:019968289</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
[[Category: Chopra, R.]] | [[Category: Chopra, R.]] | ||
[[Category: Olland, A M.]] | [[Category: Olland, A M.]] | ||
[[Category: Aspartyl protease]] | [[Category: Aspartyl protease]] | ||
[[Category: Bace1]] | [[Category: Bace1]] | ||
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[[Category: Inhibitor]] | [[Category: Inhibitor]] | ||
[[Category: Membrane]] | [[Category: Membrane]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Xray]] | [[Category: Xray]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
Revision as of 07:34, 27 July 2012
Bace1 with the aminohydantoin Compound 37
Template:ABSTRACT PUBMED 19968289
About this Structure
3inf is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Malamas MS, Erdei J, Gunawan I, Turner J, Hu Y, Wagner E, Fan K, Chopra R, Olland A, Bard J, Jacobsen S, Magolda RL, Pangalos M, Robichaud AJ. Design and synthesis of 5,5'-disubstituted aminohydantoins as potent and selective human beta-secretase (BACE1) inhibitors. J Med Chem. 2010 Feb 11;53(3):1146-58. PMID:19968289 doi:10.1021/jm901414e
