3itz: Difference between revisions
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===Crystal Structure of p38a Mitogen-Activated Protein Kinase in Complex with a Pyrazolopyridazine Inhibitor=== | ===Crystal Structure of p38a Mitogen-Activated Protein Kinase in Complex with a Pyrazolopyridazine Inhibitor=== | ||
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==About this Structure== | ==About this Structure== | ||
3ITZ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ITZ OCA]. | 3ITZ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ITZ OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:20138761</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Mitogen-activated protein kinase]] | [[Category: Mitogen-activated protein kinase]] | ||
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[[Category: Transferase]] | [[Category: Transferase]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 10 14:14:03 2010'' | ||
Revision as of 12:14, 10 March 2010
Crystal Structure of p38a Mitogen-Activated Protein Kinase in Complex with a Pyrazolopyridazine Inhibitor
Template:ABSTRACT PUBMED 20138761
About this Structure
3ITZ is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Wurz RP, Pettus LH, Henkle B, Sherman L, Plant M, Miner K, McBride HJ, Wong LM, Saris CJ, Lee MR, Chmait S, Mohr C, Hsieh F, Tasker AS. Part 2: Structure-activity relationship (SAR) investigations of fused pyrazoles as potent, selective and orally available inhibitors of p38alpha mitogen-activated protein kinase. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1680-4. Epub 2010 Jan 21. PMID:20138761 doi:10.1016/j.bmcl.2010.01.059
Page seeded by OCA on Wed Mar 10 14:14:03 2010
