3loh: Difference between revisions
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{{STRUCTURE_3loh| PDB=3loh | SCENE= }} | |||
===Structure of the insulin receptor ectodomain, including ct peptide=== | |||
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{{ABSTRACT_PUBMED_20348418}} | |||
==Disease== | |||
Known disease associated with this structure: Diabetes mellitus, insulin-resistant, with acanthosis nigricans OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Hyperinsulinemic hypoglycemia, familial, 5 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Leprechaunism OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Rabson-Mendenhall syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]] | |||
==About this Structure== | |||
3LOH is a 5 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LOH OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:20348418</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Mus musculus]] | |||
[[Category: Receptor protein-tyrosine kinase]] | |||
[[Category: Lawrence, M C.]] | |||
[[Category: Smith, B J.]] | |||
[[Category: Cell surface receptor/immune system]] | |||
[[Category: Ct peptide]] | |||
[[Category: Immune system-hormone receptor complex]] | |||
[[Category: Insulin receptor]] | |||
[[Category: Ir ectodomain]] | |||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 28 10:54:42 2010'' | |||
Revision as of 07:54, 28 April 2010
Structure of the insulin receptor ectodomain, including ct peptide
Template:ABSTRACT PUBMED 20348418
Disease
Known disease associated with this structure: Diabetes mellitus, insulin-resistant, with acanthosis nigricans OMIM:[147670], Hyperinsulinemic hypoglycemia, familial, 5 OMIM:[147670], Leprechaunism OMIM:[147670], Rabson-Mendenhall syndrome OMIM:[147670]
About this Structure
3LOH is a 5 chains structure with sequences from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA.
Reference
- Smith BJ, Huang K, Kong G, Chan SJ, Nakagawa S, Menting JG, Hu SQ, Whittaker J, Steiner DF, Katsoyannis PG, Ward CW, Weiss MA, Lawrence MC. Structural resolution of a tandem hormone-binding element in the insulin receptor and its implications for design of peptide agonists. Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):6771-6. Epub 2010 Mar 26. PMID:20348418
Page seeded by OCA on Wed Apr 28 10:54:42 2010
