3kf2: Difference between revisions
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{{STRUCTURE_3kf2| PDB=3kf2 | SCENE= }} | {{STRUCTURE_3kf2| PDB=3kf2 | SCENE= }} | ||
===The HCV NS3/NS4A protease apo structure=== | ===The HCV NS3/NS4A protease apo structure=== | ||
==About this Structure== | ==About this Structure== | ||
[[3kf2]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KF2 OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020166108</ref><references group="xtra"/><references/> | ||
[[Category: Hepacivirin]] | [[Category: Hepacivirin]] | ||
[[Category: Hepatitis c virus]] | [[Category: Hepatitis c virus]] | ||
| Line 28: | Line 17: | ||
[[Category: Ns3]] | [[Category: Ns3]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
Revision as of 02:05, 4 April 2013
The HCV NS3/NS4A protease apo structure
About this Structure
3kf2 is a 4 chain structure with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.
Reference
- Cummings MD, Lindberg J, Lin TI, de Kock H, Lenz O, Lilja E, Fellander S, Baraznenok V, Nystrom S, Nilsson M, Vrang L, Edlund M, Rosenquist A, Samuelsson B, Raboisson P, Simmen K. Induced-fit binding of the macrocyclic noncovalent inhibitor TMC435 to its HCV NS3/NS4A protease target. Angew Chem Int Ed Engl. 2010 Feb 22;49(9):1652-5. PMID:20166108 doi:10.1002/anie.200906696