3kee: Difference between revisions
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{{STRUCTURE_3kee| PDB=3kee | SCENE= }} | {{STRUCTURE_3kee| PDB=3kee | SCENE= }} | ||
===HCV NS3/NS4A complexed with Non-covalent macrocyclic compound TMC435=== | ===HCV NS3/NS4A complexed with Non-covalent macrocyclic compound TMC435=== | ||
==About this Structure== | ==About this Structure== | ||
[[3kee]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KEE OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020166108</ref><references group="xtra"/><references/> | ||
[[Category: Hepacivirin]] | [[Category: Hepacivirin]] | ||
[[Category: Hepatitis c virus]] | [[Category: Hepatitis c virus]] | ||
| Line 30: | Line 19: | ||
[[Category: Ns4a]] | [[Category: Ns4a]] | ||
[[Category: Tmc435]] | [[Category: Tmc435]] | ||
Revision as of 02:24, 4 April 2013
HCV NS3/NS4A complexed with Non-covalent macrocyclic compound TMC435
About this Structure
3kee is a 8 chain structure with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.
Reference
- Cummings MD, Lindberg J, Lin TI, de Kock H, Lenz O, Lilja E, Fellander S, Baraznenok V, Nystrom S, Nilsson M, Vrang L, Edlund M, Rosenquist A, Samuelsson B, Raboisson P, Simmen K. Induced-fit binding of the macrocyclic noncovalent inhibitor TMC435 to its HCV NS3/NS4A protease target. Angew Chem Int Ed Engl. 2010 Feb 22;49(9):1652-5. PMID:20166108 doi:10.1002/anie.200906696