3ae0: Difference between revisions
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{{STRUCTURE_3ae0| PDB=3ae0 | SCENE= }} | |||
===Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with geranylgeranyl thiopyrophosphate=== | |||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | ==About this Structure== | ||
3AE0 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AE0 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:18276850</ref><ref group="xtra">PMID:19456099</ref><references group="xtra"/> | |||
[[Category: Staphylococcus aureus]] | |||
[[Category: Jeng, W Y.]] | |||
[[Category: Liu, C I.]] | |||
[[Category: Oldfield, E.]] | |||
[[Category: Wang, A H.J.]] | |||
[[Category: Carotenoid biosynthesis]] | |||
[[Category: Crtm]] | |||
[[Category: Geranylgeranyl thiopyrophosphate]] | |||
[[Category: Ggspp]] | |||
[[Category: Head-to-head condensation]] | |||
[[Category: Staphyloxanthin biosynthesis]] | |||
[[Category: Transferase]] | |||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 24 14:12:31 2010'' | |||
Revision as of 11:01, 24 November 2010
Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with geranylgeranyl thiopyrophosphate
About this Structure
3AE0 is a 2 chains structure with sequences from Staphylococcus aureus. Full crystallographic information is available from OCA.
Reference
- Liu CI, Liu GY, Song Y, Yin F, Hensler ME, Jeng WY, Nizet V, Wang AH, Oldfield E. A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence. Science. 2008 Mar 7;319(5868):1391-4. Epub 2008 Feb 14. PMID:18276850
- Song Y, Liu CI, Lin FY, No JH, Hensler M, Liu YL, Jeng WY, Low J, Liu GY, Nizet V, Wang AH, Oldfield E. Inhibition of staphyloxanthin virulence factor biosynthesis in Staphylococcus aureus: in vitro, in vivo, and crystallographic results. J Med Chem. 2009 Jul 9;52(13):3869-80. PMID:19456099 doi:10.1021/jm9001764
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