Citrate Synthase: Difference between revisions

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==The Structure and Mechanism of Citrate Synthase==
==The Structure and Mechanism of Citrate Synthase==
{{STRUCTURE_1cts |  PDB=1cts  | SCENE= }}Citrate synthase is an enzyme active in the mitochondria, where it is responsible for catalyzing the first reaction of the citric acid cycle (Krebs Cycle): the condensation of acetyl-CoA and oxaloacetate to form citrate.
<applet load='1cts' size='300' color='white' frame='true' align='right' caption='Citrate Synthase Open Form' name='open'/>
<applet load='2cts' size='300' color='white' frame='true' align='right' caption='Citrate Synthase Closed Form' name='closed'/>Citrate synthase is an enzyme active in the mitochondria, where it is responsible for catalyzing the first reaction of the citric acid cycle (Krebs Cycle): the condensation of acetyl-CoA and oxaloacetate to form citrate.
    
    
'''Structure:''' Citrate synthase is a single amino acid chain <scene name='Daniel_Eddelman_Sandbox_2/Cts_open_monomer/1'>monomer</scene>.  Biologically, however, it exists as a  
'''Structure:''' Citrate synthase is a single amino acid chain <scene name='Daniel_Eddelman_Sandbox_2/Cts_open_monomer/1'>monomer</scene>.  Biologically, however, it exists as a  
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<references/>
<references/>
<applet load='2cts' size='250' color='white' frame='true' align='center'  caption='Citrate Synthase Closed Form' name='closed'/>