Collagen Structure & Function

Introduction

Collagen is a member of a naturally occurring protein family. In nature is is found in animals and is responsible for a variety of biological functions.

Molecular Structure

Collagen takes the form of a triple helix which is stabilized by hydrogen bonding. Each helix is enclosed by a hydration cylinder.

Collagen-Related Disorders

There are currently close to 30 different types of collagen that have been identified. The most abundant type of collagen present in the human body is that of Type I.

• Type I- found in bones,tendons,organs
• Type II-found mainly in cartilage
• Type III-found mainly in reticular fibres
• Type IV-present in the basement membrane of cell membranes
• Type V-common in hair

spinqualitylabelsall models Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D load='1cag' size='350' frame='false' scene=
1cag, resolution 1.85Å (default scene)
Ligands:	ACY
Non-Standard Residues:	HYP
Resources:	FirstGlance, OCA, PDBsum, RCSB
Coordinates:	save as pdb, mmCIF, xml

Proteopedia Page Contributors and Editors (what is this?)

Daman K. Kandola, Andrea Gorrell, Alexander Berchansky, Luis Netto, David Canner