Ubiquitin Structure & Function: Difference between revisions
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Ubiquitin is one of the most highly conserved eukaryotic proteins. Primary structures found throughout ubiquitin are identical in all bovine, insects and human ubiquitin. The only difference observed amongst these species is seen in the terminal Gly-Gly residues. Yeast and oat ubiquitin only differ in three of the 76 residues when compared to ubiquitin found in higher eukaryotes. | Ubiquitin is one of the most highly conserved eukaryotic proteins. Primary structures found throughout ubiquitin are identical in all bovine, insects and human ubiquitin. The only difference observed amongst these species is seen in the terminal Gly-Gly residues. Yeast and oat ubiquitin only differ in three of the 76 residues when compared to ubiquitin found in higher eukaryotes. | ||
Ubiquitin can not only be found in the nucleus, but in the cytoplasm and cell-surface membrane as well. | Ubiquitin can not only be found in the nucleus, but in the cytoplasm and cell-surface membrane as well. | ||
Put structure in with intro... | |||
=Function= | =Function= | ||
At first, ubiquitin was believed to be a hormone involed in inducing the differentiation of lymphocytes and activating adenylate cyclase <ref>Vijay-Kumar, S., Begg, CE., Wilkinson, KD and Cook, WJ. 1985. Three-dimensional structure of ubiquitin of 2.8 angstrom resolution. ''Proc Natl Acad Sci'' 82:3582-3585</ref>. | |||
