Sandbox 154: Difference between revisions

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= F-Actin =  
= F-Actin =  
'''Filamentous actin''' ('''F-actin''') is also referred to as [http://en.wikipedia.org/wiki/microfilaments/ microfilament] <ref> Microfilament - Wikipedia, the free encyclopedia. http://en.wikipedia.org/wiki/Microfilaments. Date accessed: March 16th, 2010. </ref> and is a highly conserved proteinous component found near ubiquitously in eukaryotic cytoskeletons. F-actin and other [http://en.wikipedia.org/wiki/actin/ actin] proteins generally provide a structural role to the cell.  
'''Filamentous actin''' ('''F-actin''') is also referred to as [http://en.wikipedia.org/wiki/microfilaments/ microfilament] <ref> Microfilament - Wikipedia, the free encyclopedia. http://en.wikipedia.org/wiki/Microfilaments. Date accessed: March 16th, 2010. </ref> and is a highly conserved proteinous component found near ubiquitously in eukaryotic cytoskeletons. F-actin and other [http://en.wikipedia.org/wiki/actin/ actin] proteins generally provide a structural role to the cell.  
= History =
== History ==
 
The F-actin structure was discovered by Straub in 1942. The structure was speculated based on a low-resolution x-ray crystallograph found in 1990 by Holmes et al. The structure was deposited in the PDB databank in Decemeber 2008 by Oda et al. <ref> Oda T, Iwasa M, Aihara T, Maéda Y, and Narita A. 2009. The nature of the globular-to fibrous actin transition. Nature,457(7228):441-445. PMID: [http://www.ncbi.nlm.nih.gov/pubmed/19158791/ 19158791]</ref>.  
The F-actin structure was discovered by Straub in 1942. The structure was speculated based on a low-resolution x-ray crystallograph found in 1990 by Holmes et al. The structure was deposited in the PDB databank in Decemeber 2008 by Oda et al. <ref> Oda T, Iwasa M, Aihara T, Maéda Y, and Narita A. 2009. The nature of the globular-to fibrous actin transition. Nature,457(7228):441-445. PMID: [http://www.ncbi.nlm.nih.gov/pubmed/19158791/ 19158791]</ref>.  




= Introduction =
== Introduction ==





Revision as of 22:59, 25 March 2010

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2zwh, resolution 3.30Å (default scene)
Ligands: ADP, CA
Non-Standard Residues: HIC


Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml


F-Actin

Filamentous actin (F-actin) is also referred to as microfilament [1] and is a highly conserved proteinous component found near ubiquitously in eukaryotic cytoskeletons. F-actin and other actin proteins generally provide a structural role to the cell.

History

The F-actin structure was discovered by Straub in 1942. The structure was speculated based on a low-resolution x-ray crystallograph found in 1990 by Holmes et al. The structure was deposited in the PDB databank in Decemeber 2008 by Oda et al. [2].


Introduction

References

  1. ↑ Microfilament - Wikipedia, the free encyclopedia. https://en.wikipedia.org/wiki/Microfilaments. Date accessed: March 16th, 2010.
  2. ↑ Oda T, Iwasa M, Aihara T, Maéda Y, and Narita A. 2009. The nature of the globular-to fibrous actin transition. Nature,457(7228):441-445. PMID: 19158791



Filamentous Actin (F-actin)

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This thing in the middle


Apparently Globular Actin (G-actin)

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Please do NOT make changes to this Sandbox until after April 23, 2010. Sandboxes 151-200 are reserved until then for use by the Chemistry 307 class at UNBC taught by Prof. Andrea Gorrell.