Pilin: Difference between revisions

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==Introduction==

Type IV pili play an important role in the pathogenesis of many bacterial species; they are a required component for the adhesion of ~~the~~ bacteria to their target cells~~. Similarly, the type IVb pilus of ''Salmonella typhi'' is the adhesion factor that allows the pathogen to enter into the gastrointestinal cells of animals <ref name=journal1>PMID:19626704</ref>~~. They may also mediate transformation, modulate target-cell specificity and play a role in twitching motility <ref name=~~journal2~~>Asha M. Balakrishna,Yvonne Yih-Wan Tan, Henry Yu-Keung Mok,Anand M. Saxena,and Kunchithapadam Swaminathan. Crystallization and preliminary X-ray diffraction analysis of Salmonella typhi PilS. 2006 October 1; 62(Pt 10): 1024–1026</ref>.

Type IV pili play an important role in the pathogenesis of many bacterial species; they are a required component for the adhesion of bacteria to their target cells. They may also mediate transformation, modulate target-cell specificity and play a role in twitching motility <ref name=journal1>Asha M. Balakrishna,Yvonne Yih-Wan Tan, Henry Yu-Keung Mok,Anand M. Saxena,and Kunchithapadam Swaminathan. Crystallization and preliminary X-ray diffraction analysis of Salmonella typhi PilS. 2006 October 1; 62(Pt 10): 1024–1026</ref>. The type IVb pilus of ''Salmonella typhi'' is the adhesion factor that allows the pathogen to enter into the gastrointestinal cells of animals <ref name=journal2>PMID:19626704</ref>.

==Structure==

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 <br>
 ==Introduction==
-Type IV pili play an important role in the pathogenesis of many bacterial species; they are a required component for the adhesion of the bacteria to their target cells. Similarly, the type IVb pilus of ''Salmonella typhi'' is the adhesion factor that allows the pathogen to enter into the gastrointestinal cells of animals <ref name=journal1>PMID:19626704</ref>. They may also mediate transformation, modulate target-cell specificity and play a role in twitching motility <ref name=journal2>Asha M. Balakrishna,Yvonne Yih-Wan Tan, Henry Yu-Keung Mok,Anand M. Saxena,and Kunchithapadam Swaminathan. Crystallization and preliminary X-ray diffraction analysis of Salmonella typhi PilS. 2006 October 1; 62(Pt 10): 1024–1026</ref>.
+Type IV pili play an important role in the pathogenesis of many bacterial species; they are a required component for the adhesion of bacteria to their target cells. They may also mediate transformation, modulate target-cell specificity and play a role in twitching motility <ref name=journal1>Asha M. Balakrishna,Yvonne Yih-Wan Tan, Henry Yu-Keung Mok,Anand M. Saxena,and Kunchithapadam Swaminathan. Crystallization and preliminary X-ray diffraction analysis of Salmonella typhi PilS. 2006 October 1; 62(Pt 10): 1024–1026</ref>. The type IVb pilus of ''Salmonella typhi'' is the adhesion factor that allows the pathogen to enter into the gastrointestinal cells of animals <ref name=journal2>PMID:19626704</ref>.
 ==Structure==