Interleukin-10: Difference between revisions
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===Crystal structure of human IL-10=== | ===Crystal structure of human IL-10=== | ||
Interleukin 10 is a ternary complex that requires specific assembly for proper function. The IL-10 complex is composed of IL-10,IL-10R1,IL-10R2. The initial step is the formation of IL-10 and IL-10R1 generating a conformational change that is required for IL-10R2 to be able to associate and form the ternary complex. | Interleukin 10 is a ternary complex that requires specific assembly for proper function. The IL-10 complex is composed of IL-10,IL-10R1,IL-10R2. The initial step is the formation of IL-10 and IL-10R1 generating a conformational change that is required for IL-10R2 to be able to associate and form the ternary complex <ref>PMID:16982608</ref>. | ||
=='''IL-10'''== | =='''IL-10'''== | ||
Interleukin-10 is in the class [http://en.wikipedia.org/wiki/Cytokine cytokine].<ref>PMID:16982608</ref> Interleukin-10 is a very powerful anti-inflammatory cytokine that is most commonly found to be produce by moncytes <ref>PMID:15772682</ref>. IL-10 has the ability to be a immunosupressive as well as a anti-angiogenic this means that it has the ability both promot and inhibit tumors<ref>PMID:16122836</ref>. | Interleukin-10 is in the class [http://en.wikipedia.org/wiki/Cytokine cytokine].<ref>PMID:16982608</ref> Interleukin-10 is a very powerful anti-inflammatory cytokine that is most commonly found to be produce by moncytes <ref>PMID:15772682</ref>. IL-10 has the ability to be a immunosupressive as well as a anti-angiogenic this means that it has the ability both promot and inhibit tumors<ref>PMID:16122836</ref>. | ||
