Sandbox 181: Difference between revisions

Line 14:

[[Image:Glutathione reductase.png|thumb|alt=Alt text|Glutathione Reductase]]

It is a thermostable protein as it retains 100% of its function up to 65 degrees Celsius attributing to the importance of its function in the cell <ref>PMID: 2044390</ref>. It is encoded by a single gene ([http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=summary&list_uids=2936 GeneID:2936], ~~MIM138300~~) located on chromosome 8p21.1 <ref name="kelner">PMID:10708558</ref>. It consists of 13 exons spanning 50kb<ref name="kelner"/>

It is a thermostable protein as it retains 100% of its function up to 65 degrees Celsius attributing to the importance of its function in the cell <ref>PMID: 2044390</ref>. It is encoded by a single gene ([http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=summary&list_uids=2936 GeneID:2936], [http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=138300 MIM 138300]) located on chromosome 8p21.1 <ref name="kelner">PMID:10708558</ref>. It consists of 13 exons spanning 50kb<ref name="kelner"/>

==Topology==

GSH reductase has a central five-stranded parallel beta-sheet (beta1, beta2, beta3, beta7 and beta8) <ref name="Dym">PMID:11514662</ref>. This central beta-sheet is surrounded by alpha-helices 1 and 2 with a crossover connection of a three-stranded antiparallel beta-sheet (beta4-6).

Sandbox 181: Difference between revisions

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 14: / Line 14: @@
 [[Image:Glutathione reductase.png|thumb|alt=Alt text|Glutathione Reductase]]
-It is a thermostable protein as it retains 100% of its function up to 65 degrees Celsius attributing to the importance of its function in the cell <ref>PMID: 2044390</ref>. It is encoded by a single gene ([http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=summary&list_uids=2936 GeneID:2936], MIM138300) located on chromosome 8p21.1 <ref name="kelner">PMID:10708558</ref>. It consists of 13 exons spanning 50kb<ref name="kelner"/>
+It is a thermostable protein as it retains 100% of its function up to 65 degrees Celsius attributing to the importance of its function in the cell <ref>PMID: 2044390</ref>. It is encoded by a single gene ([http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=summary&list_uids=2936 GeneID:2936], [http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=138300 MIM 138300]) located on chromosome 8p21.1 <ref name="kelner">PMID:10708558</ref>. It consists of 13 exons spanning 50kb<ref name="kelner"/>
 ==Topology==
 GSH reductase has a central five-stranded parallel beta-sheet (beta1, beta2, beta3, beta7 and beta8) <ref name="Dym">PMID:11514662</ref>. This central beta-sheet is surrounded by alpha-helices 1 and 2 with a crossover connection of a three-stranded antiparallel beta-sheet (beta4-6).