Birrer Sandbox 2: Difference between revisions
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==Overview== | ==Overview== | ||
Alcohol dehydrogenase (ADH) is an enzyme that catalyzes the 4th step in the metabolism of fructose before glycolysis. In the 4th step, glyceraldehyde is converted to the glycolytic intermediate DHAP by the NADH-dependent reduction to glycerol, which is catalyzed by alcohol dehydrogenase. ADH (PDB id [[1htb]]) catalyzes the oxidation of primary and secondary alcohols to their corresponding aldehydes and ketones through a mechanism that involves the removal of hydrogen. | Alcohol dehydrogenase (ADH) is an enzyme that catalyzes the 4th step in the metabolism of fructose before glycolysis. In the 4th step, glyceraldehyde is converted to the glycolytic intermediate DHAP by the NADH-dependent reduction to glycerol, which is catalyzed by alcohol dehydrogenase.<ref>Voet, et. al. ''Fundamentals of Biochemistry: 3rd Edition''. Hoboken: Wiley & Sons, Inc, 2008.</ref> ADH (PDB id [[1htb]]) catalyzes the oxidation of primary and secondary alcohols to their corresponding aldehydes and ketones through a mechanism that involves the removal of hydrogen. | ||