Titin Structure & Function: Difference between revisions
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Titin that is intact has been found to be important for normal muscle structure and function.<ref name=journal1/> This was observed when titin mutation disrupted the sacromere assembly and function, an example would be mutations that affect the I-band portion of titin would change the elasticity of muscle.<ref name=journal1/> | Titin that is intact has been found to be important for normal muscle structure and function.<ref name=journal1/> This was observed when titin mutation disrupted the sacromere assembly and function, an example would be mutations that affect the I-band portion of titin would change the elasticity of muscle.<ref name=journal1/> | ||
Titin has also been found to be linked with chromosomes, having a key role in mitosis.<ref name=journal4/> During mitosis, titin control the axial diameter of mitotic chromosomes.<ref name=journal4/> | Titin has also been found to be linked with chromosomes, having a key role in mitosis.<ref name=journal4/> During mitosis, titin control the axial diameter of mitotic chromosomes.<ref name=journal4/> | ||
==Structure Related to Function== | |||
Titin is a fairly linear protein with a reasoning to why the structure is that way. Titin being a filamentous shaped protein is able to its job in striated muscles.<ref name=journal4/> The molecules are formed with bands themselves and when they form sacromeres they line up next to one another in a linear fashion. The way the structure is the only reason why it can work as an elastic for muscles for when they contract and release. | |||
= References = | = References = | ||
<references/> | <references/> | ||
