3h0j: Difference between revisions
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[[Image:3h0j.png|left|200px]] | |||
[[Image:3h0j. | |||
{{STRUCTURE_3h0j| PDB=3h0j | SCENE= }} | {{STRUCTURE_3h0j| PDB=3h0j | SCENE= }} | ||
===Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase in complex with compound 2=== | ===Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase in complex with compound 2=== | ||
{{ABSTRACT_PUBMED_20219367}} | {{ABSTRACT_PUBMED_20219367}} | ||
==About this Structure== | ==About this Structure== | ||
[[3h0j]] is a 3 chain structure of [[Acetyl-CoA carboxylase]] and [[Biotin carboxylase]] with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H0J OCA]. | |||
==See Also== | |||
*[[Acetyl-CoA carboxylase|Acetyl-CoA carboxylase]] | |||
*[[Biotin carboxylase|Biotin carboxylase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020219367</ref><references group="xtra"/> | ||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: Tong, L.]] | [[Category: Tong, L.]] | ||
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[[Category: Carboxyltransferase]] | [[Category: Carboxyltransferase]] | ||
[[Category: Ct]] | [[Category: Ct]] | ||
[[Category: Fatty acid biosynthesis]] | [[Category: Fatty acid biosynthesis]] | ||
[[Category: Inhibitor]] | [[Category: Inhibitor]] | ||
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[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 10:13, 25 July 2012
Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase in complex with compound 2
Template:ABSTRACT PUBMED 20219367
About this Structure
3h0j is a 3 chain structure of Acetyl-CoA carboxylase and Biotin carboxylase with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.
See Also
Reference
- Corbett JW, Freeman-Cook KD, Elliott R, Vajdos F, Rajamohan F, Kohls D, Marr E, Zhang H, Tong L, Tu M, Murdande S, Doran SD, Houser JA, Song W, Jones CJ, Coffey SB, Buzon L, Minich ML, Dirico KJ, Tapley S, McPherson RK, Sugarman E, Harwood HJ Jr, Esler W. Discovery of small molecule isozyme non-specific inhibitors of mammalian acetyl-CoA carboxylase 1 and 2. Bioorg Med Chem Lett. 2010 Apr 1;20(7):2383-8. Epub 2009 Apr 24. PMID:20219367 doi:10.1016/j.bmcl.2009.04.091