3exo: Difference between revisions

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{{Seed}}
[[Image:3exo.png|left|200px]]
[[Image:3exo.png|left|200px]]


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{{STRUCTURE_3exo|  PDB=3exo  |  SCENE=  }}  
{{STRUCTURE_3exo|  PDB=3exo  |  SCENE=  }}  


===Crystal structure of BACE1 bound to inhibitor===
===Crystal structure of BACE1 bound to inhibitor===


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{{ABSTRACT_PUBMED_19036583}}
{{ABSTRACT_PUBMED_19036583}}


==About this Structure==
==About this Structure==
3EXO is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EXO OCA].  
[[3exo]] is a 1 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EXO OCA].  
 
==See Also==
*[[Beta secretase|Beta secretase]]


==Reference==
==Reference==
<ref group="xtra">PMID:19036583</ref><references group="xtra"/>
<ref group="xtra">PMID:019036583</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Memapsin 2]]
[[Category: Memapsin 2]]
[[Category: Allison, T J.]]
[[Category: Allison, T J.]]
[[Category: Alternative splicing]]
[[Category: Aspartyl protease]]
[[Category: Aspartyl protease]]
[[Category: Bace 1]]
[[Category: Bace 1]]
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[[Category: Transmembrane]]
[[Category: Transmembrane]]
[[Category: Zymogen]]
[[Category: Zymogen]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 14 08:58:07 2010''

Revision as of 04:22, 27 July 2012

File:3exo.png

Template:STRUCTURE 3exo

Crystal structure of BACE1 bound to inhibitor

Template:ABSTRACT PUBMED 19036583

About this Structure

3exo is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Steele TG, Hills ID, Nomland AA, de Leon P, Allison T, McGaughey G, Colussi D, Tugusheva K, Haugabook SJ, Espeseth AS, Zuck P, Graham SL, Stachel SJ. Identification of a small molecule beta-secretase inhibitor that binds without catalytic aspartate engagement. Bioorg Med Chem Lett. 2009 Jan 1;19(1):17-20. Epub 2008 Nov 13. PMID:19036583 doi:10.1016/j.bmcl.2008.11.027

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