3m5e: Difference between revisions

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'''Unreleased structure'''
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[[Image:3m5e.jpg|left|200px]]


The entry 3m5e is ON HOLD until Paper Publication
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{{STRUCTURE_3m5e|  PDB=3m5e  |  SCENE=  }}


Authors: Grazulis, S., Manakova, E., Golovenko, D.
===Crystal structure of human carbonic anhydrase isozyme II with 4-{[N-(6-chloro-5-formyl-2-methylthiopyrimidin-4-yl)amino]methyl}benzenesulfonamide===


Description: Crystal structure of human carbonic anhydrase isozyme II with 4-{[N-(6-chloro-5-formyl-2-methylthiopyrimidin-4-yl)amino]methyl}benzenesulfonamide


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{{ABSTRACT_PUBMED_20889345}}
 
==About this Structure==
3M5E is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M5E OCA].
 
==Reference==
<ref group="xtra">PMID:20889345</ref><references group="xtra"/>
[[Category: Carbonate dehydratase]]
[[Category: Homo sapiens]]
[[Category: Golovenko, D.]]
[[Category: Grazulis, S.]]
[[Category: Manakova, E.]]
[[Category: Carbonic anhydrase]]
[[Category: Drug design]]
[[Category: Lyase]]
[[Category: Metal-binding]]
[[Category: Sulfonamide]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 20 06:36:51 2010''

Revision as of 03:26, 20 October 2010

File:3m5e.jpg

Template:STRUCTURE 3m5e

Crystal structure of human carbonic anhydrase isozyme II with 4-{[N-(6-chloro-5-formyl-2-methylthiopyrimidin-4-yl)amino]methyl}benzenesulfonamide

Template:ABSTRACT PUBMED 20889345

About this Structure

3M5E is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Sudzius J, Baranauskiene L, Golovenko D, Matuliene J, Michailoviene V, Torresan J, Jachno J, Sukackaite R, Manakova E, Grazulis S, Tumkevicius S, Matulis D. 4-[N-(Substituted 4-pyrimidinyl)amino]benzenesulfonamides as inhibitors of carbonic anhydrase isozymes I, II, VII, and XIII. Bioorg Med Chem. 2010 Nov 1;18(21):7413-21. Epub 2010 Sep 8. PMID:20889345 doi:10.1016/j.bmc.2010.09.011

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