3mhc: Difference between revisions
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New page: '''Unreleased structure''' The entry 3mhc is ON HOLD Authors: Avvaru, B.S. Description: Crystal structure of human cabonic anhydrase II in adduct with an adamantyl analogue of acetazol... |
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===Crystal structure of human cabonic anhydrase II in adduct with an adamantyl analogue of acetazolamide in a novel hydrophobic binding pocket=== | |||
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==About this Structure== | |||
3MHC is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MHC OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:20605094</ref><references group="xtra"/> | |||
[[Category: Carbonate dehydratase]] | |||
[[Category: Homo sapiens]] | |||
[[Category: Avvaru, B S.]] | |||
[[Category: Acetazolamide]] | |||
[[Category: Adamantyl]] | |||
[[Category: Carbonic anhydrase inhibitor]] | |||
[[Category: Lyase]] | |||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 21 10:19:14 2010'' | |||
Revision as of 06:12, 21 July 2010
Crystal structure of human cabonic anhydrase II in adduct with an adamantyl analogue of acetazolamide in a novel hydrophobic binding pocket
Template:ABSTRACT PUBMED 20605094
About this Structure
3MHC is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Avvaru BS, Wagner JM, Maresca A, Scozzafava A, Robbins AH, Supuran CT, McKenna R. Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors. Bioorg Med Chem Lett. 2010 Aug 1;20(15):4376-81. Epub 2010 Jun 17. PMID:20605094 doi:10.1016/j.bmcl.2010.06.082
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