Conservation, Evolutionary: Difference between revisions
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ConSurf-DB's analysis is done with sophisticated, published, peer-reviewed, state of the art methods. A more detailed overview of the [[ConSurfDB_vs._ConSurf#ConSurf-DB_Process|process employed by ConSurf-DB]] is available. Proteopedia's built-in display of ConSurf-DB results is a good place to start looking for conserved patches. | ConSurf-DB's analysis is done with sophisticated, published, peer-reviewed, state of the art methods. A more detailed overview of the [[ConSurfDB_vs._ConSurf#ConSurf-DB_Process|process employed by ConSurf-DB]] is available. Proteopedia's built-in display of ConSurf-DB results is a good place to start looking for conserved patches. | ||
However, as explained [[#ConSurf-DB Usually Hides Some Functional Sites|below]], ConSurf-DB usually does not show all the conserved patches present in proteins with the same function. Therefore, you may wish to extend your analysis of conservation by limiting the analysis to proteins of one function, using the ConSurf Server, as explained [[#Limiting Conservation Analysis to Proteins of a Single Function|below]]. The results of such an analysis can be displayed in a molecular scene in Proteopedia. See | However, as explained [[#ConSurf-DB Usually Hides Some Functional Sites|below]], ConSurf-DB usually does not show all the conserved patches present in proteins with the same function. Therefore, you may wish to extend your analysis of conservation by limiting the analysis to proteins of one function, using the ConSurf Server, as explained [[#Limiting Conservation Analysis to Proteins of a Single Function|below]]. The results of such an analysis can be displayed in a molecular scene in Proteopedia. See [[Help:How to Insert a ConSurf Result Into a Proteopedia Green Link]]. | ||
==Locating Variable Patches== | ==Locating Variable Patches== | ||
