3l38: Difference between revisions
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[[Image:3l38.png|left|200px]] | |||
[[Image:3l38. | |||
{{STRUCTURE_3l38| PDB=3l38 | SCENE= }} | {{STRUCTURE_3l38| PDB=3l38 | SCENE= }} | ||
===Bace1 in complex with the aminopyridine Compound 44=== | ===Bace1 in complex with the aminopyridine Compound 44=== | ||
{{ABSTRACT_PUBMED_20223661}} | {{ABSTRACT_PUBMED_20223661}} | ||
==About this Structure== | ==About this Structure== | ||
[[3l38]] is a 1 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L38 OCA]. | |||
==See Also== | |||
*[[Beta secretase|Beta secretase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020223661</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
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[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
Revision as of 22:37, 25 July 2012
Bace1 in complex with the aminopyridine Compound 44
Template:ABSTRACT PUBMED 20223661
About this Structure
3l38 is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Malamas MS, Barnes K, Hui Y, Johnson M, Lovering F, Condon J, Fobare W, Solvibile W, Turner J, Hu Y, Manas ES, Fan K, Olland A, Chopra R, Bard J, Pangalos MN, Reinhart P, Robichaud AJ. Novel pyrrolyl 2-aminopyridines as potent and selective human beta-secretase (BACE1) inhibitors. Bioorg Med Chem Lett. 2010 Apr 1;20(7):2068-73. Epub 2010 Feb 23. PMID:20223661 doi:10.1016/j.bmcl.2010.02.075
