3loh: Difference between revisions

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{{Seed}}
[[Image:3loh.png|left|200px]]
[[Image:3loh.jpg|left|200px]]


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{{STRUCTURE_3loh|  PDB=3loh  |  SCENE=  }}  
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===Structure of the insulin receptor ectodomain, including ct peptide===
===Structure of the insulin receptor ectodomain, including ct peptide===


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{{ABSTRACT_PUBMED_20348418}}
{{ABSTRACT_PUBMED_20348418}}


==Disease==
==About this Structure==
Known disease associated with this structure: Diabetes mellitus, insulin-resistant, with acanthosis nigricans OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Hyperinsulinemic hypoglycemia, familial, 5 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Leprechaunism OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Rabson-Mendenhall syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]]
[[3loh]] is a 5 chain structure of [[Hormone]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LOH OCA].


==About this Structure==
==See Also==
3LOH is a 5 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LOH OCA].
*[[Hormone|Hormone]]


==Reference==
==Reference==
<ref group="xtra">PMID:20348418</ref><references group="xtra"/>
<ref group="xtra">PMID:020348418</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Insulin receptor]]
[[Category: Insulin receptor]]
[[Category: Ir ectodomain]]
[[Category: Ir ectodomain]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 28 10:54:42 2010''

Revision as of 08:56, 26 July 2012

File:3loh.png

Template:STRUCTURE 3loh

Structure of the insulin receptor ectodomain, including ct peptide

Template:ABSTRACT PUBMED 20348418

About this Structure

3loh is a 5 chain structure of Hormone with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA.

See Also

Reference

  1. Smith BJ, Huang K, Kong G, Chan SJ, Nakagawa S, Menting JG, Hu SQ, Whittaker J, Steiner DF, Katsoyannis PG, Ward CW, Weiss MA, Lawrence MC. Structural resolution of a tandem hormone-binding element in the insulin receptor and its implications for design of peptide agonists. Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):6771-6. Epub 2010 Mar 26. PMID:20348418

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