User:Reuben Chacko: Difference between revisions
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This protein maintains a reducing environment inside cells by reducing glutathione disulfide to glutathione. Glutathione reductase or GSR catalyzes this reaction by attacking glutahione disulfide nucleophilically via the Cys63 residue. The Cys63 nucleophile itself is generated by the nucleophilic attack of | This protein maintains a reducing environment inside cells by reducing glutathione disulfide to glutathione. Glutathione reductase or GSR catalyzes this reaction by attacking glutahione disulfide nucleophilically via the Cys63 residue. The Cys63 nucleophile itself is generated by the nucleophilic attack of | ||
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<applet load='1wat' size='[450,338]' frame='true' align='right' | |||
caption='Aspartate receptor ligand binding domain (1wat)' scene='User:Reuben_Chacko/Glutathione_reductase/2>Ribbon representation of glutathione reductase showing glutathione disulfide (molecule with two yellow spheres) and FAD with its flat flavin moiety sitting up-close ready to carry out the nucleophilic attack.</scene> | |||
