3ld6: Difference between revisions
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===Crystal structure of human lanosterol 14alpha-demethylase (CYP51) in complex with ketoconazole=== | ===Crystal structure of human lanosterol 14alpha-demethylase (CYP51) in complex with ketoconazole=== | ||
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==About this Structure== | ==About this Structure== | ||
3LD6 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3i3k 3i3k]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LD6 OCA]. | 3LD6 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3i3k 3i3k]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LD6 OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:20149798</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Sterol 14-demethylase]] | [[Category: Sterol 14-demethylase]] | ||
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[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu May 20 08:58:41 2010'' | ||
Revision as of 05:58, 20 May 2010
Crystal structure of human lanosterol 14alpha-demethylase (CYP51) in complex with ketoconazole
Template:ABSTRACT PUBMED 20149798
About this Structure
3LD6 is a 2 chains structure with sequences from Homo sapiens. This structure supersedes the now removed PDB entry 3i3k. Full crystallographic information is available from OCA.
Reference
- Strushkevich N, Usanov SA, Park HW. Structural basis of human CYP51 inhibition by antifungal azoles. J Mol Biol. 2010 Apr 9;397(4):1067-78. Epub 2010 Feb 10. PMID:20149798 doi:10.1016/j.jmb.2010.01.075
Page seeded by OCA on Thu May 20 08:58:41 2010
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Sterol 14-demethylase
- Arrowsmith, C H.
- Bountra, C.
- Edwards, A M
- MacKenzie, F.
- Park, H.
- SGC, Structural Genomics Consortium.
- Strushkevich, N.
- Tempel, W.
- Weigelt, J.
- Alternative splicing
- Cholesterol biosynthesis
- Cytochrome p450
- Endoplasmic reticulum
- Heme
- Iron
- Ketoconazole
- Lipid synthesis
- Membrane
- Metal-binding
- Microsome
- Monooxygenase
- Nadp
- Oxidoreductase
- Polymorphism
- Sgc
- Steroid biosynthesis
- Sterol 14alpha-demethylase
- Sterol biosynthesis
- Structural genomic
- Structural genomics consortium
- Transmembrane
