3l0v: Difference between revisions

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{{Seed}}
[[Image:3l0v.png|left|200px]]
[[Image:3l0v.png|left|200px]]


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{{STRUCTURE_3l0v|  PDB=3l0v  |  SCENE=  }}  
{{STRUCTURE_3l0v|  PDB=3l0v  |  SCENE=  }}  


===Crystal structure of catalytic domain of TACE with the first hydantoin inhibitor occupying the S1' pocket===
===Crystal structure of catalytic domain of TACE with the first hydantoin inhibitor occupying the S1' pocket===


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{{ABSTRACT_PUBMED_20172725}}
{{ABSTRACT_PUBMED_20172725}}


==About this Structure==
==About this Structure==
3L0V is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L0V OCA].  
[[3l0v]] is a 2 chain structure of [[A Disintegrin And Metalloproteinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L0V OCA].  
 
==See Also==
*[[A Disintegrin And Metalloproteinase|A Disintegrin And Metalloproteinase]]


==Reference==
==Reference==
<ref group="xtra">PMID:20172725</ref><references group="xtra"/>
<ref group="xtra">PMID:020172725</ref><references group="xtra"/>
[[Category: ADAM 17 endopeptidase]]
[[Category: ADAM 17 endopeptidase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Notch signaling pathway]]
[[Category: Notch signaling pathway]]
[[Category: Protease]]
[[Category: Protease]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May  5 11:11:44 2010''

Revision as of 23:18, 26 July 2012

File:3l0v.png

Template:STRUCTURE 3l0v

Crystal structure of catalytic domain of TACE with the first hydantoin inhibitor occupying the S1' pocket

Template:ABSTRACT PUBMED 20172725

About this Structure

3l0v is a 2 chain structure of A Disintegrin And Metalloproteinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Yu W, Guo Z, Orth P, Madison V, Chen L, Dai C, Feltz RJ, Girijavallabhan VM, Kim SH, Kozlowski JA, Lavey BJ, Li D, Lundell D, Niu X, Piwinski JJ, Popovici-Muller J, Rizvi R, Rosner KE, Shankar BB, Shih NY, Siddiqui MA, Sun J, Tong L, Umland S, Wong MK, Yang DY, Zhou G. Discovery and SAR of hydantoin TACE inhibitors. Bioorg Med Chem Lett. 2010 Mar 15;20(6):1877-80. Epub 2010 Feb 4. PMID:20172725 doi:10.1016/j.bmcl.2010.01.148

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