3lgf: Difference between revisions

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{{Seed}}
[[Image:3lgf.png|left|200px]]
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{{STRUCTURE_3lgf|  PDB=3lgf  |  SCENE=  }}  
{{STRUCTURE_3lgf|  PDB=3lgf  |  SCENE=  }}  
===Crystal structure of the 53BP1 tandem tudor domain in complex with p53K370me2===
===Crystal structure of the 53BP1 tandem tudor domain in complex with p53K370me2===
{{ABSTRACT_PUBMED_20307547}}


==Disease==
[[http://www.uniprot.org/uniprot/TP53B_HUMAN TP53B_HUMAN]] Note=A chromosomal aberration involving TP53BP1 is found in a form of myeloproliferative disorder chronic with eosinophilia. Translocation t(5;15)(q33;q22) with PDGFRB creating a TP53BP1-PDGFRB fusion protein.


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==Function==
The line below this paragraph, {{ABSTRACT_PUBMED_20307547}}, adds the Publication Abstract to the page
[[http://www.uniprot.org/uniprot/TP53B_HUMAN TP53B_HUMAN]] Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation.<ref>PMID:12364621</ref><ref>PMID:17190600</ref>  
(as it appears on PubMed at http://www.pubmed.gov), where 20307547 is the PubMed ID number.
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{{ABSTRACT_PUBMED_20307547}}


==About this Structure==
==About this Structure==
3LGF is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LGF OCA].  
[[3lgf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LGF OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:20307547</ref><references group="xtra"/>
<ref group="xtra">PMID:020307547</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Kutateladze, T G.]]
[[Category: Kutateladze, T G.]]
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[[Category: Transcription]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
[[Category: Transcription regulation]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 12 10:37:38 2010''
Retrieved from "https://proteopedia.org/3lgf"