3klt: Difference between revisions
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{{STRUCTURE_3klt| PDB=3klt | SCENE= }} | {{STRUCTURE_3klt| PDB=3klt | SCENE= }} | ||
===Crystal structure of a vimentin fragment=== | ===Crystal structure of a vimentin fragment=== | ||
{{ABSTRACT_PUBMED_20176112}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/VIME_HUMAN VIME_HUMAN]] Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.<ref>PMID:21746880</ref> Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2.<ref>PMID:21746880</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3klt]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KLT OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020176112</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Nicolet, S.]] | [[Category: Nicolet, S.]] | ||
| Line 29: | Line 16: | ||
[[Category: 2a]] | [[Category: 2a]] | ||
[[Category: Alpha-helix]] | [[Category: Alpha-helix]] | ||
[[Category: Coiled-coil]] | [[Category: Coiled-coil]] | ||
[[Category: Intermediate filament]] | [[Category: Intermediate filament]] | ||
| Line 36: | Line 22: | ||
[[Category: Structural protein]] | [[Category: Structural protein]] | ||
[[Category: Vimentin]] | [[Category: Vimentin]] | ||
Revision as of 02:15, 4 April 2013
Crystal structure of a vimentin fragment
Template:ABSTRACT PUBMED 20176112
Function
[VIME_HUMAN] Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.[1] Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2.[2]
About this Structure
3klt is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Nicolet S, Herrmann H, Aebi U, Strelkov SV. Atomic structure of vimentin coil 2. J Struct Biol. 2010 May;170(2):369-76. Epub 2010 Feb 20. PMID:20176112 doi:10.1016/j.jsb.2010.02.012
- ↑ Challa AA, Stefanovic B. A novel role of vimentin filaments: binding and stabilization of collagen mRNAs. Mol Cell Biol. 2011 Sep;31(18):3773-89. doi: 10.1128/MCB.05263-11. Epub 2011 Jul , 11. PMID:21746880 doi:10.1128/MCB.05263-11
- ↑ Challa AA, Stefanovic B. A novel role of vimentin filaments: binding and stabilization of collagen mRNAs. Mol Cell Biol. 2011 Sep;31(18):3773-89. doi: 10.1128/MCB.05263-11. Epub 2011 Jul , 11. PMID:21746880 doi:10.1128/MCB.05263-11
