User:Wayne Decatur/Haloarcula Large Ribosomal Subunit: Difference between revisions
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:*With no significant portion of the 50S subunit appearing topologically separate or capable of forming a stable structure on its own, the solved structure of the 1.6-million Dalton large subunit is '''<font color="#3a3a3a">one massive domain</font>'''. | :*With no significant portion of the 50S subunit appearing topologically separate or capable of forming a stable structure on its own, the solved structure of the 1.6-million Dalton large subunit is '''<font color="#3a3a3a">one massive domain</font>'''. | ||
:*On the other hand, the large subunit's partner in translation, [[User:Wayne Decatur/Sandbox Thermus Small Ribosomal Subunit|the small subunit (30S)]], clearly has three domains. | :*On the other hand, the large subunit's partner in translation, [[User:Wayne Decatur/Sandbox Thermus Small Ribosomal Subunit|the small subunit (30S)]], clearly has three domains. | ||
:*It is important to note that two stalks (the L1 stalk and L7/L12 stalk) seen in lower resolution structures on each side of the large ribosomal subunit at lower resolution <ref>PMID: 9657144</ref> are not visible in the higher resolution structure viewed here. Thus, ''in actuality'' the Haloarcula large subunit has a less monolithic appearance with other protuberances on either side of the central one, yet clearly not possessing the distinct domains formed by the distinct rRNA domains visible in the secondary structure (see below). | :*It is important to note that two stalks (the L1 stalk and L7/L12 stalk) seen in lower resolution structures on each side of the large ribosomal subunit at lower resolution<ref>PMID: 9657144</ref> are not visible in the higher resolution structure viewed here. Thus, ''in actuality'' the Haloarcula large subunit has a less monolithic appearance with other protuberances on either side of the central one, yet clearly not possessing the distinct domains formed by the distinct rRNA domains visible in the secondary structure (see below). | ||
:<scene name='User:Wayne_Decatur/Sandbox_Haloarcula_Ribosomal_Large_Subunit/1s72drums/3'>The large ribosomal subunit</scene> is a '''<font color="#fd0162">ribonucleo</font><font color="#cbbe8a">protein</font>''' macromolecule. | :<scene name='User:Wayne_Decatur/Sandbox_Haloarcula_Ribosomal_Large_Subunit/1s72drums/3'>The large ribosomal subunit</scene> is a '''<font color="#fd0162">ribonucleo</font><font color="#cbbe8a">protein</font>''' macromolecule. | ||
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:#a small <font color="magenta">'''5S rRNA'''</font> (122 nucleotides)which forms part of the central protuberance seen in the large subunit. | :#a small <font color="magenta">'''5S rRNA'''</font> (122 nucleotides)which forms part of the central protuberance seen in the large subunit. | ||
:#a large <font color="#fd0162">'''23S rRNA'''</font> (3045 nucleotides) - 2833 of the 3045 nucleotides of the <font color="#fd0162">23S rRNA</font> are seen in the structure. | :#a large <font color="#fd0162">'''23S rRNA'''</font> (3045 nucleotides) - 2833 of the 3045 nucleotides of the <font color="#fd0162">23S rRNA</font> are seen in the structure. | ||
===The rRNA domains:=== | ===The rRNA domains:=== | ||
