3mtl: Difference between revisions

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===Crystal structure of the PCTAIRE1 kinase in complex with Indirubin E804===

==Function==

[[http://www.uniprot.org/uniprot/CDK16_HUMAN CDK16_HUMAN]] Protein kinase that plays a role in vesicle-mediated transport processes and exocytosis. Regulates GH1 release by brain neurons. Phosphorylates NSF, and thereby regulates NSF oligomerization. Required for normal spermatogenesis. Regulates neuron differentiation and dendrite development (By similarity). Plays a role in the regulation of insulin secretion in response to changes in blood glucose levels. Can phosphorylate CCNY at 'Ser-336' (in vitro).<ref>PMID:22796189</ref> <ref>PMID:22798068</ref> <ref>PMID:22184064</ref>

==About this Structure==

~~3MTL~~ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MTL OCA].

[[3mtl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MTL OCA].

==Reference==

[[Category: Cyclin-dependent kinase]]

[[Category: Homo sapiens]]

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[[Category: Structural genomics consortium]]

[[Category: Transferase]]

~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 10 11:16:14 2010''~~

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-{{Seed}}
-[[Image:3mtl.jpg|left|200px]]
-<!--
-The line below this paragraph, containing "STRUCTURE_3mtl", creates the "Structure Box" on the page.
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-or leave the SCENE parameter empty for the default display.
--->
 {{STRUCTURE_3mtl|  PDB=3mtl  |  SCENE=  }}
 ===Crystal structure of the PCTAIRE1 kinase in complex with Indirubin E804===
+==Function==
+[[http://www.uniprot.org/uniprot/CDK16_HUMAN CDK16_HUMAN]] Protein kinase that plays a role in vesicle-mediated transport processes and exocytosis. Regulates GH1 release by brain neurons. Phosphorylates NSF, and thereby regulates NSF oligomerization. Required for normal spermatogenesis. Regulates neuron differentiation and dendrite development (By similarity). Plays a role in the regulation of insulin secretion in response to changes in blood glucose levels. Can phosphorylate CCNY at 'Ser-336' (in vitro).<ref>PMID:22796189</ref> <ref>PMID:22798068</ref> <ref>PMID:22184064</ref>
 ==About this Structure==
-MTL is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MTL OCA].
+[[3mtl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MTL OCA].
+==Reference==
+<references group="xtra"/><references/>
 [[Category: Cyclin-dependent kinase]]
 [[Category: Homo sapiens]]
@@ Line 53: / Line 48: @@
 [[Category: Structural genomics consortium]]
 [[Category: Transferase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 10 11:16:14 2010''