3mvm: Difference between revisions
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===P38 Alpha Map Kinase complexed with pyrrolotriazine inhibitor 7V=== | |||
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{{ABSTRACT_PUBMED_20804198}} | |||
==About this Structure== | |||
3MVM is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MVM OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:20804198</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Mitogen-activated protein kinase]] | |||
[[Category: Sack, J S.]] | |||
[[Category: Kinase]] | |||
[[Category: P38 map kinase]] | |||
[[Category: Serine/threonine-protein kinase]] | |||
[[Category: Transferase]] | |||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 13 10:47:55 2010'' | |||
Revision as of 07:38, 13 October 2010
P38 Alpha Map Kinase complexed with pyrrolotriazine inhibitor 7V
Template:ABSTRACT PUBMED 20804198
About this Structure
3MVM is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Liu C, Lin J, Wrobleski ST, Lin S, Hynes J, Wu H, Dyckman AJ, Li T, Wityak J, Gillooly KM, Pitt S, Shen DR, Zhang RF, McIntyre KW, Salter-Cid L, Shuster DJ, Zhang H, Marathe PH, Doweyko AM, Sack JS, Kiefer SE, Kish KF, Newitt JA, McKinnon M, Dodd JH, Barrish JC, Schieven GL, Leftheris K. Discovery of 4-(5-(cyclopropylcarbamoyl)-2-methylphenylamino)-5-methyl-N-propylpyrrolo[ 1,2-f][1,2,4]triazine-6-carboxamide (BMS-582949), a clinical p38alpha MAP kinase inhibitor for the treatment of inflammatory diseases. J Med Chem. 2010 Sep 23;53(18):6629-39. PMID:20804198 doi:10.1021/jm100540x
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