3nau: Difference between revisions

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{{Seed}}
[[Image:3nau.jpg|left|200px]]
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{{STRUCTURE_3nau|  PDB=3nau  |  SCENE=  }}  
{{STRUCTURE_3nau|  PDB=3nau  |  SCENE=  }}  
===Crystal structure of ZHX2 HD2 (zinc-fingers and homeoboxes protein 2, homeodomain 2)===
===Crystal structure of ZHX2 HD2 (zinc-fingers and homeoboxes protein 2, homeodomain 2)===
{{ABSTRACT_PUBMED_20509910}}


 
==Function==
<!--
[[http://www.uniprot.org/uniprot/ZHX2_HUMAN ZHX2_HUMAN]] Acts as a transcriptional repressor. Represses the promoter activity of the CDC25C gene stimulated by NFYA.<ref>PMID:12741956</ref>
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{{ABSTRACT_PUBMED_20509910}}


==About this Structure==
==About this Structure==
3NAU is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NAU OCA].  
[[3nau]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NAU OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:20509910</ref><references group="xtra"/>
<ref group="xtra">PMID:020509910</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Bird, L E.]]
[[Category: Bird, L E.]]
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[[Category: Transcription]]
[[Category: Transcription]]
[[Category: Zhx2]]
[[Category: Zhx2]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul  7 08:43:15 2010''

Revision as of 20:50, 17 April 2013

Template:STRUCTURE 3nau

Crystal structure of ZHX2 HD2 (zinc-fingers and homeoboxes protein 2, homeodomain 2)

Template:ABSTRACT PUBMED 20509910

Function

[ZHX2_HUMAN] Acts as a transcriptional repressor. Represses the promoter activity of the CDC25C gene stimulated by NFYA.[1]

About this Structure

3nau is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Bird LE, Ren J, Nettleship JE, Folkers GE, Owens RJ, Stammers DK. Novel structural features in two ZHX homeodomains derived from a systematic study of single and multiple domains. BMC Struct Biol. 2010 May 28;10:13. PMID:20509910 doi:10.1186/1472-6807-10-13
  1. ↑ Kawata H, Yamada K, Shou Z, Mizutani T, Yazawa T, Yoshino M, Sekiguchi T, Kajitani T, Miyamoto K. Zinc-fingers and homeoboxes (ZHX) 2, a novel member of the ZHX family, functions as a transcriptional repressor. Biochem J. 2003 Aug 1;373(Pt 3):747-57. PMID:12741956 doi:10.1042/BJ20030171

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