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The Chemistry of Drugs in Forensic Science
The Chemistry of Drugs in Forensic Science
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What does the term DRUG mean
Drugs vs. Medicines
Drugs - Natural or synthetic compounds potentially used for physiological and psychological effects.
        Medicinal Uses - to correct or help some physiological or psychological problem
        Drug Abuse - chemicals used/taken for purposes for which they were never intended.
Metabolic Poisons affect Biochemical Mechanisms. Examples of this class of poisons
Carbon Monoxide (Gas) - colorless, odorless, toxic - suicide or homocide.
Binds to iron in hemoglobin and only very slowly is released - displacing oxygen - Carboxyhemoglobin is 140 time more stable than oxyhemoglobin
Breathing 0.1% CO in air for 4 hours converts 60% of hemoglobin to carboxyhemoglobin!
CO produced by incomplete combustion - 200 million tons in US annually
Not a cumulative poison (given time, the free hemoglobin is released)

Revision as of 11:00, 13 July 2010

The Chemistry of Drugs in Forensic Science



What does the term DRUG mean

Drugs vs. Medicines

Drugs - Natural or synthetic compounds potentially used for physiological and psychological effects.

       Medicinal Uses - to correct or help some physiological or psychological problem
       Drug Abuse - chemicals used/taken for purposes for which they were never intended.

Metabolic Poisons affect Biochemical Mechanisms. Examples of this class of poisons

Carbon Monoxide (Gas) - colorless, odorless, toxic - suicide or homocide. Binds to iron in hemoglobin and only very slowly is released - displacing oxygen - Carboxyhemoglobin is 140 time more stable than oxyhemoglobin Breathing 0.1% CO in air for 4 hours converts 60% of hemoglobin to carboxyhemoglobin! CO produced by incomplete combustion - 200 million tons in US annually Not a cumulative poison (given time, the free hemoglobin is released)