1t7j: Difference between revisions

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{{Seed}}
[[Image:1t7j.png|left|200px]]
[[Image:1t7j.png|left|200px]]


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{{STRUCTURE_1t7j|  PDB=1t7j  |  SCENE=  }}  
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===crystal structure of inhibitor amprenavir in complex with a multi-drug resistant variant of HIV-1 protease (L63P/V82T/I84V)===
===crystal structure of inhibitor amprenavir in complex with a multi-drug resistant variant of HIV-1 protease (L63P/V82T/I84V)===


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{{ABSTRACT_PUBMED_15771427}}
{{ABSTRACT_PUBMED_15771427}}


==About this Structure==
==About this Structure==
1T7J is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T7J OCA].  
[[1t7j]] is a 2 chain structure of [[Virus protease]] with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T7J OCA].  
 
==See Also==
*[[Virus protease|Virus protease]]


==Reference==
==Reference==
<ref group="xtra">PMID:15771427</ref><references group="xtra"/>
<ref group="xtra">PMID:015771427</ref><references group="xtra"/>
[[Category: HIV-1 retropepsin]]
[[Category: HIV-1 retropepsin]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
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[[Category: Substrate envelope]]
[[Category: Substrate envelope]]
[[Category: Thermodynamic]]
[[Category: Thermodynamic]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 21 09:51:15 2010''

Revision as of 20:43, 26 July 2012

File:1t7j.png

Template:STRUCTURE 1t7j

crystal structure of inhibitor amprenavir in complex with a multi-drug resistant variant of HIV-1 protease (L63P/V82T/I84V)

Template:ABSTRACT PUBMED 15771427

About this Structure

1t7j is a 2 chain structure of Virus protease with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

See Also

Reference

  1. Surleraux DL, Tahri A, Verschueren WG, Pille GM, de Kock HA, Jonckers TH, Peeters A, De Meyer S, Azijn H, Pauwels R, de Bethune MP, King NM, Prabu-Jeyabalan M, Schiffer CA, Wigerinck PB. Discovery and selection of TMC114, a next generation HIV-1 protease inhibitor. J Med Chem. 2005 Mar 24;48(6):1813-22. PMID:15771427 doi:10.1021/jm049560p

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