2x99: Difference between revisions

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{{Seed}}
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[[Image:2x99.jpg|left|200px]]
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{{STRUCTURE_2x99|  PDB=2x99  |  SCENE=  }}  
{{STRUCTURE_2x99|  PDB=2x99  |  SCENE=  }}  


===MAPPING THE CATALYTIC CYCLE OF SCHISTOSOMA MANSONI THIOREDOXIN GLUTATHIONE REDUCTASE BY X-RAY CRYSTALLOGRAPHY===
===THIOREDOXIN GLUTATHIONE REDUCTASE FROM SCHISTOSOMA MANSONI IN COMPLEX WITH NADPH===




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[[Category: Thioredoxin]]
[[Category: Thioredoxin]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 21 10:14:35 2010''
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Revision as of 07:51, 28 July 2010

File:2x99.png

Template:STRUCTURE 2x99

THIOREDOXIN GLUTATHIONE REDUCTASE FROM SCHISTOSOMA MANSONI IN COMPLEX WITH NADPH

About this Structure

2X99 is a 1 chain structure with sequence from Schistosoma mansoni. Full crystallographic information is available from OCA.

Reference

  1. Angelucci F, Miele AE, Boumis G, Dimastrogiovanni D, Brunori M, Bellelli A. Glutathione reductase and thioredoxin reductase at the crossroad: the structure of Schistosoma mansoni thioredoxin glutathione reductase. Proteins. 2008 Aug 15;72(3):936-45. PMID:18300227 doi:10.1002/prot.21986
  2. Angelucci F, Sayed AA, Williams DL, Boumis G, Brunori M, Dimastrogiovanni D, Miele AE, Pauly F, Bellelli A. Inhibition of Schistosoma mansoni thioredoxin-glutathione reductase by auranofin: structural and kinetic aspects. J Biol Chem. 2009 Oct 16;284(42):28977-85. Epub 2009 Aug 26. PMID:19710012 doi:10.1074/jbc.M109.020701

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