3mhc: Difference between revisions
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Revision as of 07:59, 28 July 2010
Crystal structure of human cabonic anhydrase II in adduct with an adamantyl analogue of acetazolamide in a novel hydrophobic binding pocket
Template:ABSTRACT PUBMED 20605094
About this Structure
3MHC is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Avvaru BS, Wagner JM, Maresca A, Scozzafava A, Robbins AH, Supuran CT, McKenna R. Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors. Bioorg Med Chem Lett. 2010 Aug 1;20(15):4376-81. Epub 2010 Jun 17. PMID:20605094 doi:10.1016/j.bmcl.2010.06.082
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