User:Wayne Decatur/Sandbox Glutamate receptor: Difference between revisions
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===Subunit non-equivalence=== | ===Subunit non-equivalence=== | ||
<table width='220' align='left' cellpadding='2'><tr><td bgcolor='#eeeeee'><applet load='3kg2' size='220' frame='true' align='left' scene='User:Wayne_Decatur/Sandbox_Glutamate_receptor/Ac3kg2letter/1' caption='A is equivalent to C'/></td><td bgcolor='#eeeeee'><applet load='3kg2' size='220' frame='true' align='left' scene='User:Wayne_Decatur/Sandbox_Glutamate_receptor/Bd3kg2letter/1' caption='B is equivalent to D'/></td></tr></table> | <table width='220' align='left' cellpadding='2'><tr><td bgcolor='#eeeeee'><applet load='3kg2' size='220' frame='true' align='left' scene='User:Wayne_Decatur/Sandbox_Glutamate_receptor/Ac3kg2letter/1' caption='A is equivalent to C'/></td><td bgcolor='#eeeeee'><applet load='3kg2' size='220' frame='true' align='left' scene='User:Wayne_Decatur/Sandbox_Glutamate_receptor/Bd3kg2letter/1' caption='B is equivalent to D'/></td></tr></table> | ||
As a result of the swapping and symmetry mismatch, there is subunit non-equivalence; even though all the chains are the same chemically, there are two distinct conformations of the subunits. This means there are two matching pairs of subunits. The pairs are illustrated on the left and the morphs referred to below will show on the right: | |||
{{Structure | {{Structure | ||
|PDB= 3kg2 |SIZE=420|SCENE=User:Wayne_Decatur/Sandbox_Glutamate_receptor/Default3kg2/1|CAPTION= glutamate receptor ([[3kg2]]), resolution 3.6Å (<scene name='User:Wayne_Decatur/Sandbox_Glutamate_receptor/Default3kg2/1'>initial scene</scene>) | |PDB= 3kg2 |SIZE=420|SCENE=User:Wayne_Decatur/Sandbox_Glutamate_receptor/Default3kg2/1|CAPTION= glutamate receptor ([[3kg2]]), resolution 3.6Å (<scene name='User:Wayne_Decatur/Sandbox_Glutamate_receptor/Default3kg2/1'>initial scene</scene>) | ||
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kg2 OCA], [http://www.ebi.ac.uk/pdbsum/3kg2 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=3kg2 RCSB]</span> | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kg2 OCA], [http://www.ebi.ac.uk/pdbsum/3kg2 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=3kg2 RCSB]</span> | ||
}} | }} | ||
* <span style="color:forestgreen">Subunit '''A</span>''' is equivalent to <span style="color:cornflowerblue">Subunit '''C'''</span>. A morph showing the relationship of the two equivalent subunits relative the axis of their symmetry. | * <span style="color:forestgreen">Subunit '''A</span>''' is equivalent to <span style="color:cornflowerblue">Subunit '''C'''</span>. A morph showing the relationship of the two equivalent subunits relative the axis of their symmetry. | ||
* <span style="color:red">Subunit '''B</span>''' is equivalent to Subunit '''D'''.<!--<span style="color:#FFFF80">Subunit '''D'''</span> (<--says 'Subunit D' in hard-to-read gold color matching the structure)--> A morph showing the relationship of the two equivalent subunits relative the axis of their symmetry. | * <span style="color:red">Subunit '''B</span>''' is equivalent to Subunit '''D'''.<!--<span style="color:#FFFF80">Subunit '''D'''</span> (<--says 'Subunit D' in hard-to-read gold color matching the structure)--> A morph showing the relationship of the two equivalent subunits relative the axis of their symmetry. | ||
