User:Wayne Decatur/Sandbox Glutamate receptor: Difference between revisions

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* <span style="color:red">Subunit '''B</span>''' is equivalent to Subunit '''D''' (ABOVE). <!--<span style="color:#FFFF80">Subunit '''D'''</span>(<--says 'Subunit D' in hard-to-read gold color matching the structure)-->  On the right, a  <scene name='User:Wayne_Decatur/Sandbox_Glutamate_receptor/Btodmorph/5'>morph showing the equivalency of the two subunits by rotating around the axis of their symmetry</scene>.
* <span style="color:red">Subunit '''B</span>''' is equivalent to Subunit '''D''' (ABOVE). <!--<span style="color:#FFFF80">Subunit '''D'''</span>(<--says 'Subunit D' in hard-to-read gold color matching the structure)-->  On the right, a  <scene name='User:Wayne_Decatur/Sandbox_Glutamate_receptor/Btodmorph/5'>morph showing the equivalency of the two subunits by rotating around the axis of their symmetry</scene>.


However, each of the subunit '''<span style="color:forestgreen">A</span>'''/<span style="color:cornflowerblue">'''C'''</span> group though is distinct from those of the <span style="color:red">'''B</span>'''/'''D''' group. Having established the two equivalent groups we can simplify the discussion of the relationship between the two pairs by focusing solely on comparing <span style="color:forestgreen">Subunit '''A'</span>''' and <span style="color:red">Subunit '''B</span>'''.
However, each of the subunit '''<span style="color:forestgreen">A</span>'''/<span style="color:cornflowerblue">'''C'''</span> group though is distinct from those of the <span style="color:red">'''B</span>'''/'''D''' group. Having established the two equivalent groups we can simplify the discussion of the relationship between the two pairs by focusing solely on comparing <span style="color:forestgreen">Subunit '''A'</span>''' and <span style="color:red">Subunit '''B</span>'''.<br>
 
The domains themselves stay relatively static between the two conformational forms, with the linkers in between and the resulting arrangement changing. This is best illustrated by superposition of the individual domains of <span style="color:forestgreen">Subunit '''A</span>''' and <span style="color:red">Subunit '''B</span>''':
The domains themselves stay relatively static between the two conformational forms, with the linkers in between and the resulting arrangement changing. This is best illustrated by superposition of the individual domains of <span style="color:forestgreen">Subunit '''A</span>''' and <span style="color:red">Subunit '''B</span>''':
*<scene name='User:Wayne_Decatur/Sandbox_Glutamate_receptor/Atdatobsuper/2'>Superposition of the ATD</scene>.
*<scene name='User:Wayne_Decatur/Sandbox_Glutamate_receptor/Atdatobsuper/3'>Superposition of the ATD</scene>.
*Superposition of the LBD.
*Superposition of the LBD.
*Superposition of the TMD.
*Superposition of the TMD.