Fibrinogen: Difference between revisions
From Proteopedia
Jump to navigationJump to search
David Canner (talk | contribs) No edit summary |
David Canner (talk | contribs) No edit summary |
||
| Line 3: | Line 3: | ||
<applet load='3hus2.pdb' size='300' frame='true' align='right' scene="Fibrinogen/Fibrinogen_starting_scene/2" caption= 'Crystal structure of fibrinogen fragment D with the peptide ligand Gly-Pro-Arg-Pro-amide, [[3hus]]' /> | <applet load='3hus2.pdb' size='300' frame='true' align='right' scene="Fibrinogen/Fibrinogen_starting_scene/2" caption= 'Crystal structure of fibrinogen fragment D with the peptide ligand Gly-Pro-Arg-Pro-amide, [[3hus]]' /> | ||
'''Fibrinogen''' is a glycoprotein found in the blood that is converted into fibrin during blood coagulation. Fibrinogen is cleaved by another protein, [[thrombin]], exposing Knobs A & B to form fibrin. It is this fibrin that is linked to clotting factors like factor XIII which form clots to prevent excessive bleeding from wounds sustained. | '''Fibrinogen''' is a glycoprotein found in the blood that is converted into fibrin during blood coagulation. Fibrinogen is cleaved by another protein, [[thrombin]], exposing Knobs A & B to form fibrin. <ref>PMID:692730</ref> It is this fibrin that is linked to clotting factors like factor XIII which form clots to prevent excessive bleeding from wounds sustained. <ref>PMID:18673233</ref> | ||
{{TOC limit|limit=2}} | {{TOC limit|limit=2}} | ||
| Line 40: | Line 40: | ||
[[1fib]] – hFbg+Ca<br /> | [[1fib]] – hFbg+Ca<br /> | ||
[[1fic]], [[1fid]] - hFbg<br /> | [[1fic]], [[1fid]] - hFbg<br /> | ||
==References== | |||
<references /> | |||
