User:Wayne Decatur/Sandbox Glutamate receptor: Difference between revisions
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::Note that the M4 segment associates with the ion-channel core of an adjacent subunit. | ::Note that the M4 segment associates with the ion-channel core of an adjacent subunit. | ||
:{{Link Toggle FancyCartoonHighQualityView}}. | :{{Link Toggle FancyCartoonHighQualityView}}. | ||
*The TMD domain of the GluA2 receptor shares structural and sequence similarity with the pore region of the potassium (K+), as hinted at by earlier work<ref name ="pot1">PMID: 7539962</ref><ref name ="pot2">PMID: 7761417</ref><ref name =" | *The TMD domain of the GluA2 receptor shares structural and sequence similarity with the pore region of the potassium (K+), as hinted at by earlier work<ref name ="pot1">PMID: 7539962</ref><ref name ="pot2">PMID: 7761417</ref><ref name ="pot3">PMID: 9525859</ref>. Here the pore region of ''Streptomyces lividans'' potassium channel ([[1bl8]])<scene name='User:Wayne_Decatur/Sandbox_Glutamate_receptor/Gluvspottmd/4'>superposed with the TMD domain with GluA2</scene>, specifically the inner helix of the K+ channel aligned with the M3 segment. M1 also overlays well with the outer helix of the K+ channel. | ||
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[[Category: Neuron]] | [[Category: Neuron]] | ||
[[Category: Neurotransmitter]] | [[Category: Neurotransmitter]] | ||
[[Category: Potassium Channels]] | |||
[[Category: RCSB PDB Molecule of the Month]] | |||
[[Category: Streptomyces lividans]] | |||
[[Category: Cabral, J M.]] | |||
[[Category: Chait, B T.]] | |||
[[Category: Cohen, S L.]] | |||
[[Category: Doyle, D A.]] | |||
[[Category: Gulbis, J M.]] | |||
[[Category: Kuo, A.]] | |||
[[Category: Mackinnon, R.]] | |||
[[Category: Pfuetzner, R A.]] | |||
[[Category: Integral membrane protein]] | |||
[[Category: Potassium channel]] | |||
