3kot: Difference between revisions

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{{Seed}}
[[Image:3kot.png|left|200px]]
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===Structure of the Citrobacter freundii effector binding domain containing three amino acid substitutions: T103V, S221A and Y264F===
===Structure of the Citrobacter freundii effector binding domain containing three amino acid substitutions: T103V, S221A and Y264F===
{{ABSTRACT_PUBMED_20594961}}


 
==Function==
<!--
[[http://www.uniprot.org/uniprot/AMPR_CITFR AMPR_CITFR]] Regulates the expression of the beta-lactamase gene. Represses cephalosporinase (AmpC) in the presence of beta-lactams and induces it in the absence of them.  
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{{ABSTRACT_PUBMED_20594961}}


==About this Structure==
==About this Structure==
3KOT is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Citrobacter_freundii Citrobacter freundii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KOT OCA].  
[[3kot]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Citrobacter_freundii Citrobacter freundii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KOT OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:20594961</ref><references group="xtra"/>
<ref group="xtra">PMID:020594961</ref><references group="xtra"/><references/>
[[Category: Citrobacter freundii]]
[[Category: Citrobacter freundii]]
[[Category: Balcewich, M D.]]
[[Category: Balcewich, M D.]]
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[[Category: Transcription]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
[[Category: Transcription regulation]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 28 12:00:08 2010''

Revision as of 02:21, 4 April 2013

Template:STRUCTURE 3kot

Structure of the Citrobacter freundii effector binding domain containing three amino acid substitutions: T103V, S221A and Y264F

Template:ABSTRACT PUBMED 20594961

Function

[AMPR_CITFR] Regulates the expression of the beta-lactamase gene. Represses cephalosporinase (AmpC) in the presence of beta-lactams and induces it in the absence of them.

About this Structure

3kot is a 1 chain structure with sequence from Citrobacter freundii. Full crystallographic information is available from OCA.

Reference

  1. Balcewich MD, Reeve TM, Orlikow EA, Donald LJ, Vocadlo DJ, Mark BL. Crystal structure of the AmpR effector binding domain provides insight into the molecular regulation of inducible ampc beta-lactamase. J Mol Biol. 2010 Jul 30;400(5):998-1010. Epub 2010 May 31. PMID:20594961 doi:10.1016/j.jmb.2010.05.040

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