2x8g: Difference between revisions

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===OXIDIZED THIOREDOXIN GLUTATHIONE REDUCTASE FROM SCHISTOSOMA MANSONI===
===OXIDIZED THIOREDOXIN GLUTATHIONE REDUCTASE FROM SCHISTOSOMA MANSONI===


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{{ABSTRACT_PUBMED_20659890}}


==About this Structure==
==About this Structure==
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==Reference==
==Reference==
<ref group="xtra">PMID:18300227</ref><ref group="xtra">PMID:19710012</ref><references group="xtra"/>
<ref group="xtra">PMID:20659890</ref><ref group="xtra">PMID:18300227</ref><ref group="xtra">PMID:19710012</ref><references group="xtra"/>
[[Category: Schistosoma mansoni]]
[[Category: Schistosoma mansoni]]
[[Category: Thioredoxin-disulfide reductase]]
[[Category: Thioredoxin-disulfide reductase]]
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[[Category: Detoxification pathway]]
[[Category: Detoxification pathway]]
[[Category: Flavoprotein]]
[[Category: Flavoprotein]]
[[Category: Nadph]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
[[Category: Redox-active center]]
[[Category: Redox-active center]]


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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Aug 12 00:03:43 2010''

Revision as of 19:56, 11 August 2010

File:2x8g.png

Template:STRUCTURE 2x8g

OXIDIZED THIOREDOXIN GLUTATHIONE REDUCTASE FROM SCHISTOSOMA MANSONI

Template:ABSTRACT PUBMED 20659890

About this Structure

2X8G is a 1 chain structure with sequence from Schistosoma mansoni. Full crystallographic information is available from OCA.

Reference

  1. Angelucci F, Dimastrogiovanni D, Boumis G, Brunori M, Miele AE, Saccoccia F, Bellelli A. Mapping the catalytic cycle of Schistosoma mansoni thioredoxin glutathione reductase by x-ray crystallography. J Biol Chem. 2010 Jul 21. PMID:20659890 doi:10.1074/jbc.M110.141960
  2. Angelucci F, Miele AE, Boumis G, Dimastrogiovanni D, Brunori M, Bellelli A. Glutathione reductase and thioredoxin reductase at the crossroad: the structure of Schistosoma mansoni thioredoxin glutathione reductase. Proteins. 2008 Aug 15;72(3):936-45. PMID:18300227 doi:10.1002/prot.21986
  3. Angelucci F, Sayed AA, Williams DL, Boumis G, Brunori M, Dimastrogiovanni D, Miele AE, Pauly F, Bellelli A. Inhibition of Schistosoma mansoni thioredoxin-glutathione reductase by auranofin: structural and kinetic aspects. J Biol Chem. 2009 Oct 16;284(42):28977-85. Epub 2009 Aug 26. PMID:19710012 doi:10.1074/jbc.M109.020701

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