3n3g: Difference between revisions
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[[Image:3n3g.png|left|200px]] | [[Image:3n3g.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
[[3n3g]] is a 2 chain structure of [[Cathepsin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N3G OCA]. | |||
==See Also== | |||
*[[Cathepsin]] | |||
==Reference== | ==Reference== | ||
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[[Category: Covalent inhibitor]] | [[Category: Covalent inhibitor]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
Revision as of 22:43, 26 December 2010
4-(3-Trifluoromethylphenyl)-pyrimidine-2-carbonitrile as cathepsin S inhibitors: N3, not N1 is critically important
Template:ABSTRACT PUBMED 20580231
About this Structure
3n3g is a 2 chain structure of Cathepsin with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Cai J, Fradera X, van Zeeland M, Dempster M, Cameron KS, Bennett DJ, Robinson J, Popplestone L, Baugh M, Westwood P, Bruin J, Hamilton W, Kinghorn E, Long C, Uitdehaag JC. 4-(3-Trifluoromethylphenyl)-pyrimidine-2-carbonitrile as cathepsin S inhibitors: N3, not N1 is critically important. Bioorg Med Chem Lett. 2010 Aug 1;20(15):4507-10. Epub 2010 Jun 10. PMID:20580231 doi:10.1016/j.bmcl.2010.06.043
