3mk8: Difference between revisions

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{{Seed}}
[[Image:3mk8.png|left|200px]]
[[Image:3mk8.png|left|200px]]


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{{STRUCTURE_3mk8|  PDB=3mk8  |  SCENE=  }}  
{{STRUCTURE_3mk8|  PDB=3mk8  |  SCENE=  }}  


===The MCL-1 BH3 Helix is an Exclusive MCL-1 Inhibitor and Apoptosis Sensitizer===
===The MCL-1 BH3 Helix is an Exclusive MCL-1 Inhibitor and Apoptosis Sensitizer===


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{{ABSTRACT_PUBMED_20562877}}
{{ABSTRACT_PUBMED_20562877}}


==About this Structure==
==About this Structure==
3MK8 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MK8 OCA].  
[[3mk8]] is a 2 chain structure of [[Bcl-2]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MK8 OCA].  
 
==See Also==
*[[Bcl-2|Bcl-2]]


==Reference==
==Reference==
<ref group="xtra">PMID:20562877</ref><references group="xtra"/>
<ref group="xtra">PMID:020562877</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Fire, E.]]
[[Category: Fire, E.]]
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[[Category: Sahb]]
[[Category: Sahb]]
[[Category: Staple]]
[[Category: Staple]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug  4 08:27:18 2010''

Revision as of 12:43, 26 July 2012

File:3mk8.png

Template:STRUCTURE 3mk8

The MCL-1 BH3 Helix is an Exclusive MCL-1 Inhibitor and Apoptosis Sensitizer

Template:ABSTRACT PUBMED 20562877

About this Structure

3mk8 is a 2 chain structure of Bcl-2 with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Stewart ML, Fire E, Keating AE, Walensky LD. The MCL-1 BH3 helix is an exclusive MCL-1 inhibitor and apoptosis sensitizer. Nat Chem Biol. 2010 Aug;6(8):595-601. Epub 2010 Jun 20. PMID:20562877 doi:10.1038/nchembio.391

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