2xm8: Difference between revisions
From Proteopedia
Jump to navigationJump to search
New page: '''Unreleased structure''' The entry 2xm8 is ON HOLD until Paper Publication Authors: Caldwell, J.J., Welsh, E.J., Matijssen, B., Anderson, V.E., Antoni, L., Boxall, K., Urban, F., Haye... |
No edit summary |
||
| Line 1: | Line 1: | ||
[[Image:2xm8.jpg|left|200px]] | |||
The | <!-- | ||
The line below this paragraph, containing "STRUCTURE_2xm8", creates the "Structure Box" on the page. | |||
You may change the PDB parameter (which sets the PDB file loaded into the applet) | |||
or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | |||
or leave the SCENE parameter empty for the default display. | |||
--> | |||
{{STRUCTURE_2xm8| PDB=2xm8 | SCENE= }} | |||
===CO-CRYSTAL STRUCTURE OF A SMALL MOLECULE INHIBITOR BOUND TO THE KINASE DOMAIN OF CHK2=== | |||
<!-- | |||
The line below this paragraph, {{ABSTRACT_PUBMED_21186793}}, adds the Publication Abstract to the page | |||
(as it appears on PubMed at http://www.pubmed.gov), where 21186793 is the PubMed ID number. | |||
--> | |||
{{ABSTRACT_PUBMED_21186793}} | |||
==About this Structure== | |||
[[2xm8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XM8 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:21186793</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Non-specific serine/threonine protein kinase]] | |||
[[Category: Aherne, G W.]] | |||
[[Category: Anderson, V E.]] | |||
[[Category: Antoni, L.]] | |||
[[Category: Boxall, K.]] | |||
[[Category: Caldwell, J J.]] | |||
[[Category: Collins, I.]] | |||
[[Category: Garrett, M D.]] | |||
[[Category: Hayes, A.]] | |||
[[Category: Matijssen, C.]] | |||
[[Category: Oliver, A W.]] | |||
[[Category: Pearl, L H.]] | |||
[[Category: Raynaud, F I.]] | |||
[[Category: Raynham, T.]] | |||
[[Category: Rigoreau, L.]] | |||
[[Category: Urban, F.]] | |||
[[Category: Welsh, E J.]] | |||
Revision as of 05:09, 12 January 2011
CO-CRYSTAL STRUCTURE OF A SMALL MOLECULE INHIBITOR BOUND TO THE KINASE DOMAIN OF CHK2
Template:ABSTRACT PUBMED 21186793
About this Structure
2xm8 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Caldwell JJ, Welsh EJ, Matijssen C, Anderson VE, Antoni L, Boxall K, Urban F, Hayes A, Raynaud FI, Rigoreau LJ, Raynham T, Aherne GW, Pearl LH, Oliver AW, Garrett MD, Collins I. Structure-Based Design of Potent and Selective 2-(Quinazolin-2-yl)phenol Inhibitors of Checkpoint Kinase 2. J Med Chem. 2010 Dec 27. PMID:21186793 doi:10.1021/jm101150b