3o46: Difference between revisions
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{{STRUCTURE_3o46| PDB=3o46 | SCENE= }} | {{STRUCTURE_3o46| PDB=3o46 | SCENE= }} | ||
===Crystal structure of the PDZ domain of MPP7=== | ===Crystal structure of the PDZ domain of MPP7=== | ||
==Function== | |||
[[http://www.uniprot.org/uniprot/MPP7_HUMAN MPP7_HUMAN]] Acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. Involved in the assembly of protein complexes at sites of cell-cell contact.<ref>PMID:17332497</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3o46]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O46 OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Arrowsmith, C H.]] | [[Category: Arrowsmith, C H.]] | ||
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[[Category: Sgc]] | [[Category: Sgc]] | ||
[[Category: Structural genomics consortium]] | [[Category: Structural genomics consortium]] | ||
Revision as of 12:01, 24 April 2013
Crystal structure of the PDZ domain of MPP7
Function
[MPP7_HUMAN] Acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. Involved in the assembly of protein complexes at sites of cell-cell contact.[1]
About this Structure
3o46 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- ↑ Stucke VM, Timmerman E, Vandekerckhove J, Gevaert K, Hall A. The MAGUK protein MPP7 binds to the polarity protein hDlg1 and facilitates epithelial tight junction formation. Mol Biol Cell. 2007 May;18(5):1744-55. Epub 2007 Mar 1. PMID:17332497 doi:10.1091/mbc.E06-11-0980