3n1b: Difference between revisions

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{{Seed}}
[[Image:3n1b.png|left|200px]]
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{{STRUCTURE_3n1b|  PDB=3n1b  |  SCENE=  }}  
{{STRUCTURE_3n1b|  PDB=3n1b  |  SCENE=  }}  
===C-terminal domain of Vps54 subunit of the GARP complex===
===C-terminal domain of Vps54 subunit of the GARP complex===
{{ABSTRACT_PUBMED_20615984}}


==Disease==
[[http://www.uniprot.org/uniprot/VPS54_MOUSE VPS54_MOUSE]] Note=Defects in Vps54 are the cause of wobbler phenotype (wr). Wr is autosomal recessive and is a spontaneous mutation discovered almost 50 years ago. It causes spinal muscular atrophy and defective spermiogenesis.<ref>PMID:16244655</ref> 


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==Function==
The line below this paragraph, {{ABSTRACT_PUBMED_20615984}}, adds the Publication Abstract to the page
[[http://www.uniprot.org/uniprot/VPS54_MOUSE VPS54_MOUSE]] May be involved in retrograde transport from early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD (By similarity).  
(as it appears on PubMed at http://www.pubmed.gov), where 20615984 is the PubMed ID number.
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{{ABSTRACT_PUBMED_20615984}}


==About this Structure==
==About this Structure==
3N1B is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N1B OCA].  
[[3n1b]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N1B OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:20615984</ref><references group="xtra"/>
<ref group="xtra">PMID:020615984</ref><references group="xtra"/><references/>
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Abascal-Palacios, G.]]
[[Category: Abascal-Palacios, G.]]
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[[Category: Transport protein]]
[[Category: Transport protein]]
[[Category: Vesicle trafficking]]
[[Category: Vesicle trafficking]]
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Retrieved from "https://proteopedia.org/3n1b"