3kho: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_3kho| PDB=3kho | SCENE= }} | {{STRUCTURE_3kho| PDB=3kho | SCENE= }} | ||
===Crystal structure of murine Ig-beta (CD79b) homodimer=== | ===Crystal structure of murine Ig-beta (CD79b) homodimer=== | ||
{{ABSTRACT_PUBMED_20696394}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CD79B_MOUSE CD79B_MOUSE]] Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.<ref>PMID:8175787</ref> <ref>PMID:10352267</ref> <ref>PMID:12356683</ref> <ref>PMID:15661879</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3kho]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KHO OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020696394</ref><references group="xtra"/><references/> | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Radaev, S.]] | [[Category: Radaev, S.]] | ||
| Line 35: | Line 22: | ||
[[Category: Protein binding]] | [[Category: Protein binding]] | ||
[[Category: V-set]] | [[Category: V-set]] | ||