3nyp: Difference between revisions
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===A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine ligand containing bis-3-fluoropyrrolidine end side chains=== | ===A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine ligand containing bis-3-fluoropyrrolidine end side chains=== | ||
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The line below this paragraph, {{ABSTRACT_PUBMED_21221451}}, adds the Publication Abstract to the page | |||
(as it appears on PubMed at http://www.pubmed.gov), where 21221451 is the PubMed ID number. | |||
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{{ABSTRACT_PUBMED_21221451}} | |||
==About this Structure== | ==About this Structure== | ||
[[3nyp]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NYP OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:21221451</ref><references group="xtra"/> | |||
[[Category: Campbell, N H.]] | [[Category: Campbell, N H.]] | ||
[[Category: Neidle, S.]] | [[Category: Neidle, S.]] | ||
Revision as of 07:27, 30 March 2011
A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine ligand containing bis-3-fluoropyrrolidine end side chains
Template:ABSTRACT PUBMED 21221451
About this Structure
3nyp is a 2 chain structure. Full crystallographic information is available from OCA.
Reference
- Campbell NH, Smith DL, Reszka AP, Neidle S, O'Hagan D. Fluorine in medicinal chemistry: beta-fluorination of peripheral pyrrolidines attached to acridine ligands affects their interactions with G-quadruplex DNA. Org Biomol Chem. 2011 Mar 7;9(5):1328-31. Epub 2011 Jan 10. PMID:21221451 doi:10.1039/c0ob00886a