3ntb: Difference between revisions

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[[Image:3ntb.jpg|left|200px]]
[[Image:3ntb.png|left|200px]]


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===Structure of 6-methylthio naproxen analog bound to mCOX-2.===
===Structure of 6-methylthio naproxen analog bound to mCOX-2.===


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==About this Structure==
==About this Structure==
3NTB is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NTB OCA].  
3NTB is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NTB OCA].  
==Reference==
<ref group="xtra">PMID:20810665</ref><references group="xtra"/>
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Prostaglandin-endoperoxide synthase]]
[[Category: Prostaglandin-endoperoxide synthase]]
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[[Category: Prostaglandin h2 synthase]]
[[Category: Prostaglandin h2 synthase]]


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Revision as of 21:12, 17 November 2010

File:3ntb.png

Template:STRUCTURE 3ntb

Structure of 6-methylthio naproxen analog bound to mCOX-2.

Template:ABSTRACT PUBMED 20810665

About this Structure

3NTB is a 4 chains structure with sequences from Mus musculus. Full crystallographic information is available from OCA.

Reference

  1. Duggan KC, Walters MJ, Musee J, Harp JM, Kiefer JR, Oates JA, Marnett LJ. Molecular basis for cyclooxygenase inhibition by the non-steroidal anti-inflammatory drug naproxen. J Biol Chem. 2010 Nov 5;285(45):34950-9. Epub 2010 Sep 1. PMID:20810665 doi:10.1074/jbc.M110.162982

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